Structure of PDB 4jos Chain A

Receptor sequence
>4josA (length=228) Species: 484022 (Francisella philomiragia subsp. philomiragia ATCC 25017) [Search protein sequence]
MKKIAILGAMEIEIQPILQKLEKYETVEYANNKYYVANYNGIELVVAYSK
IGKVFSSLTATIMIEHFGVDALLFTGVAGGLQDLQVGDMIAATATVQHDV
DITAFGYPYGKIPISEVEIATSARILEQAKVIAKELNLNLHTGVIATGDQ
FVHSAERKDFVVKEFDAKAIEMEGASVNLICNEMNIPSFILRSISDTADG
DAPDNFDEFAKMAANRSADFVMKLVDRI
3D structure
PDB4jos Crystal structure of a putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Francisella philomiragia ATCC 25017 (Target NYSGRC-029335)
ChainA
Resolution1.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.2.2.9: adenosylhomocysteine nucleosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADE A A78 G79 F151 V152 E171 M172 D196 A198 A78 G79 F151 V152 E171 M172 D196 A198
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008782 adenosylhomocysteine nucleosidase activity
GO:0008930 methylthioadenosine nucleosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0009086 methionine biosynthetic process
GO:0009116 nucleoside metabolic process
GO:0009164 nucleoside catabolic process
GO:0019284 L-methionine salvage from S-adenosylmethionine
GO:0019509 L-methionine salvage from methylthioadenosine
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4jos, PDBe:4jos, PDBj:4jos
PDBsum4jos
PubMed
UniProtB0TZL4

[Back to BioLiP]