Structure of PDB 4jna Chain A

Receptor sequence

>4jnaA (length=296) Species: 536 (Chromobacterium violaceum) [Search protein sequence]

SPMLFDVIVIGGSHAGQSAALQIARARRRVLVIDAGARRNRFASQSHGVI
GQDGRSPDAIAADGKAQLLAYPNAQWREDSVVRAERSDAGYTLICASGQH
YRACQLVLAFGVVDELPELEGLEERWGESVFHCPYCHGYELDGGRIGVLG
SGPLSYLSAMLMPEWGQTVFLTDASFEPDEEQREALARRGVEIVRDRIAR
IVDRATVELADGRRIAFDGLFTMNRMRLSSPVAEQLGCAIEEGPLGPYVR
TDDAMETSTPGVFACGDITHRGGTVALAIGNGALAGIAAHRKLVFG

3D structure

PDB

4jna The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.

Chain

Resolution

2.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	I331 R335	I287 R291
BS02	peptide	A	C177 H314 R315 G316	C133 H270 R271 G272
BS03	FAD	A	S57 H58 A59 I77 D78 A79 A81 R83 N84 S90 H91 S124 V125 F154 C180 H181 G310 D311 G317 T318 V319	S13 H14 A15 I33 D34 A35 A37 R39 N40 S46 H47 S80 V81 F110 C136 H137 G266 D267 G273 T274 V275

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0004791	thioredoxin-disulfide reductase (NADPH) activity
GO:0016491	oxidoreductase activity

	Biological Process
GO:0045454	cell redox homeostasis
GO:0098869	cellular oxidant detoxification

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Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:4jna, PDBe:4jna, PDBj:4jna
PDBsum	4jna
PubMed	24553401
UniProt	A4ZPY8

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