Structure of PDB 4jiz Chain A

Receptor sequence
>4jizA (length=172) Species: 9606 (Homo sapiens) [Search protein sequence]
NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSA
GPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVP
FPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFF
VQEFNLIDRRELAPLQELIEKL
3D structure
PDB4jiz Activation of the yeast Hippo pathway by phosphorylation-dependent assembly of signaling complexes.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R71 E73 Y74 H75 K84 P85 K132 R136 R53 E55 Y56 H57 K66 P67 K114 R118
BS02 ZN A C58 C63 H140 H145 C40 C45 H122 H127
External links
PDB RCSB:4jiz, PDBe:4jiz, PDBj:4jiz
PDBsum4jiz
PubMed23579499
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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