Structure of PDB 4jhd Chain A

Receptor sequence
>4jhdA (length=371) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
VAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYV
GDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVL
LTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLD
SGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTE
EREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELKDGQVITIGNER
FRCPEALFQPSFLGMEACGIHETTYNSIMKCDVDIRKDLYANTVLSGGTT
MYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQ
MWISKQEYDESGPSIVHRKCF
3D structure
PDB4jhd Structural basis of actin filament nucleation by tandem w domains.
ChainA
Resolution2.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A G13 S14 G15 M16 K18 G156 D157 G158 G182 K213 E214 G302 M305 Y306 G9 S10 G11 M12 K14 G152 D153 G154 G178 K209 E210 G298 M301 Y302
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000281 mitotic cytokinesis
GO:0006338 chromatin remodeling
GO:0007291 sperm individualization
GO:0030723 ovarian fusome organization
GO:0032507 maintenance of protein location in cell
GO:0035148 tube formation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0031011 Ino80 complex
GO:0035060 brahma complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4jhd, PDBe:4jhd, PDBj:4jhd
PDBsum4jhd
PubMed23727244
UniProtP10987|ACT1_DROME Actin-5C (Gene Name=Act5C)

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