Structure of PDB 4je6 Chain A

Receptor sequence
>4je6A (length=193) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
DLPEIVASGDPVLHEKAREVDPGEIGSERIQKIIDDMIKVMRLAPCVGLA
APQIGVPLRIIVLEDTKEYISYAPKEEILAQERRHFDLMVMVNPVLKERS
NKKALFFEGCESVDGFRAAVERYLEVVVTGYDRQGKRIEVNASGWQARIL
QHECDHLDGNLYVDKMVPRTFRTVDNLDLPLAEGCPKLGSHHH
3D structure
PDB4je6 Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G49 Q54 C111 E112 H153 E154 H157
Catalytic site (residue number reindexed from 1) G48 Q53 C110 E111 H152 E153 H156
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C111 H153 H157 C110 H152 H156
Gene Ontology
Molecular Function
GO:0042586 peptide deformylase activity

View graph for
Molecular Function
External links
PDB RCSB:4je6, PDBe:4je6, PDBj:4je6
PDBsum4je6
PubMed24531459
UniProtQ9FV53|DEF1A_ARATH Peptide deformylase 1A, chloroplastic/mitochondrial (Gene Name=PDF1A)

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