Structure of PDB 4jc0 Chain A

Receptor sequence
>4jc0A (length=424) Species: 2336 (Thermotoga maritima) [Search protein sequence]
RVGIKVLGCPKNEADCEVLAGVLREGGHEIVFDVKDADVVVLDTCAFIED
AKRESIDEIFSFVDAKDQYGYKLVVKGCLVQRYYEELKKEIPEVDQWIGV
ADPEEIANAIETDLVPDRYRKRIDLEERPYAYVKISDGCDRGCTFCSIPS
FKGSLRSRSIEDITREVEDLLKEGKKEIILVAQDTTSYGIDLYRKQALPD
LLRRLNSLNGEFWIRVMYLHPDHLTEEIISAMLELDKVVKYFDVPVQHGS
DKILKLMGRTKSSEELKKMLSSIRERFPDAVLRTSIIVGFPGETEEDFEE
LKQFVEEIQFDKLGAFVYSDEEGTVAFNLKEKVDPEMAKRRQEELLLLQA
EISNSRLDRFVGKKLKFLVEGKEGKFLVGRTWTEAPEVDGVVFVRGKGKI
GDFLEVVIKEHDEYDMWGSVILEH
3D structure
PDB4jc0 Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases.
ChainA
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.8.4.4: [ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FS5 A G9 C10 K12 N13 C46 A47 I49 C79 C148 R150 C152 C155 I157 Q192 G8 C9 K11 N12 C45 A46 I48 C78 C139 R141 C143 C146 I148 Q183
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0035596 methylthiotransferase activity
GO:0035599 aspartic acid methylthiotransferase activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0103039 protein methylthiotransferase activity
Biological Process
GO:0006400 tRNA modification
GO:0018339 peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4jc0, PDBe:4jc0, PDBj:4jc0
PDBsum4jc0
PubMed23542644
UniProtQ9X2H6|RIMO_THEMA Ribosomal protein uS12 methylthiotransferase RimO (Gene Name=rimO)

[Back to BioLiP]