Structure of PDB 4j9h Chain A

Receptor sequence
>4j9hA (length=59) Species: 9606 (Homo sapiens) [Search protein sequence]
DPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWV
PSNYITPVN
3D structure
PDB4j9h Crystallization by capillary counter-diffusion and structure determination of the N114A mutant of the SH3 domain of Abl tyrosine kinase complexed with a high-affinity peptide ligand.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y70 S75 D77 E98 W99 W110 N114 Y115 Y9 S14 D16 E37 W38 W49 N53 Y54
External links
PDB RCSB:4j9h, PDBe:4j9h, PDBj:4j9h
PDBsum4j9h
PubMed
UniProtP00519|ABL1_HUMAN Tyrosine-protein kinase ABL1 (Gene Name=ABL1)

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