Structure of PDB 4j8u Chain A

Receptor sequence
>4j8uA (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB4j8u Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
ChainA
Resolution2.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A R40 Y41 R42 T45 R63 R72 R83 F84 S86 R116 V117 T118 R3 Y4 R5 T8 R26 R35 R46 F47 S49 R79 V80 T81
BS02 dna A R40 Y41 R42 G44 V46 R49 R63 K64 L65 P66 R69 R3 Y4 R5 G7 V9 R12 R26 K27 L28 P29 R32
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:4j8u, PDBe:4j8u, PDBj:4j8u
PDBsum4j8u
PubMed
UniProtP84233|H32_XENLA Histone H3.2

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