Structure of PDB 4j8s Chain A

Receptor sequence
>4j8sA (length=180) Species: 9606 (Homo sapiens) [Search protein sequence]
QQTDLSQVWPEANQHFSKEIDDEANSYFQRIYNHPPHPTMSVDEVLEMLQ
RFKDSTIKREREVFNCMLRNLFEEYRFFPQYPDKELHITACLFGGIIEKG
LVTYMALGLALRYVLEALRKPFGSKMYYFGIAALDRFKNRLKDYPQYCQH
LASISHFMQFPHHLQEYIEYGQQSRDPPVK
3D structure
PDB4j8s Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E825 N839 F842 Q843 N884 E888 F891 Q894 Y895 P896 E11 N25 F28 Q29 N70 E74 F77 Q80 Y81 P82
Gene Ontology
Biological Process
GO:0017148 negative regulation of translation
Cellular Component
GO:0030015 CCR4-NOT core complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4j8s, PDBe:4j8s, PDBj:4j8s
PDBsum4j8s
PubMed23644599
UniProtA5YKK6|CNOT1_HUMAN CCR4-NOT transcription complex subunit 1 (Gene Name=CNOT1)

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