Structure of PDB 4j7q Chain A

Receptor sequence
>4j7qA (length=322) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KNLINIDKPIKELPASIAIPKEKPLTGEQQKMYDEVLKHFSNPDLKVYTS
EKNKSEDDLKPLEEEEKAWLTRECFLRYLRATKWVLKDCIDRITMTLAWR
REFGISHLGEEHGDKITADLVAVENESGKQVILGYENDARPILYLKPGRQ
NTKTSHRQVQHLVFMLERVIDFMPAGQDSLALLIDFKDYPDVPKVPGVGK
EVLHILQTHYPERLGKALLTNIPWLAWTFLKLIHPFIDPLTREKLVFDEP
FVKYVPKNELDSLYGGDLKFKYNHDVYWPALVETAREKRDHYFKRFQSFG
GIVGLSEVDLRGTHEKLLYPVK
3D structure
PDB4j7q Structural determinants for phosphatidylinositol recognition by Sfh3 and substrate-induced dimer-monomer transition during lipid transfer cycles.
ChainA
Resolution1.55 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B7N A A96 R107 Q165 Q173 L177 V225 L229 Y233 E235 R236 L237 A249 A81 R92 Q150 Q158 L162 V202 L206 Y210 E212 R213 L214 A226
BS02 B7N A F252 L255 I256 F229 L232 I233
Gene Ontology
Molecular Function
GO:0008526 phosphatidylinositol transfer activity
GO:0032934 sterol binding
GO:0042802 identical protein binding
Biological Process
GO:0006869 lipid transport
GO:0008654 phospholipid biosynthetic process
GO:0009410 response to xenobiotic stimulus
GO:0015914 phospholipid transport
GO:0016126 sterol biosynthetic process
GO:0043942 negative regulation of sexual sporulation resulting in formation of a cellular spore
GO:0120009 intermembrane lipid transfer
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0071561 nucleus-vacuole junction
GO:0071944 cell periphery
GO:1902556 phosphatidylinositol transporter complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4j7q, PDBe:4j7q, PDBj:4j7q
PDBsum4j7q
PubMed23603387
UniProtP53860|PDR16_YEAST Phosphatidylinositol transfer protein PDR16 (Gene Name=PDR16)

[Back to BioLiP]