Structure of PDB 4j4m Chain A

Receptor sequence
>4j4mA (length=195) Species: 103944 (Protobothrops mucrosquamatus) [Search protein sequence]
RFPQRYVMLAIVADHGMVTKYSGNSSAITTRVHQMVSHVTEMYSPLNIAT
TLSLLRIWSSKDLITVQSDSSVTLGSFGDWRKVVLLSQQAHDCAFLNTAT
ALDDSTIGLAYSNGMCDPKFSVGLVQDHSSNVFMVAVTMTHELGHNLGMA
HDECSSCIMSPAASSGPSKLFSDCSKDDYQTFLTNTNPQCILNAP
3D structure
PDB4j4m Crystal structure of a Trimeresurus mucrosquamatus venom metalloproteinase providing new insights into the inhibition by endogenous tripeptide inhibitors.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H144 H148 H154 H141 H145 H151
BS02 ZN A D72 D106 D69 D103
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4j4m, PDBe:4j4m, PDBj:4j4m
PDBsum4j4m
PubMed23732127
UniProtU3KRG1|VM1T1_PROMU Snake venom metalloproteinase TM-1

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