Structure of PDB 4j2w Chain A

Receptor sequence
>4j2wA (length=383) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSI
NLAISARGIDALKSIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYGEA
INSINRSVLNNSLLDELEKSTTELKFGHKLVKIEWTDDKQICHFAIGTPH
TEKYDFVIGCDGAYSATRSQMQRKVEMDFSQEYMNLRYIELYIPPTEEFK
PNYGGNFAIAPDHLHIWPRHKFMLIALANSDGSFTSTFFGSKDQISDLIT
SKSRVREFLIENFPDIINIMDLDDAVKRFITYPKESLVCVNCKPYDVPGG
KAILLGDAAHAMVPFYGQGMNCGFEDVRILMALLKKHSGDRSRAFTEYTQ
TRHKDLVSITELAKRNYKEMSHDVTSKRFLLRK
3D structure
PDB4j2w Structural basis of kynurenine 3-monooxygenase inhibition.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.9: kynurenine 3-monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A I8 G9 G11 V13 D32 F33 S49 L52 A53 R109 L133 D168 G169 Y195 G313 D314 Q325 G326 M327 N328 I8 G9 G11 V13 D32 F33 S49 L52 A53 R106 L130 D161 G162 Y188 G306 D307 Q318 G319 M320 N321
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4j2w, PDBe:4j2w, PDBj:4j2w
PDBsum4j2w
PubMed23575632
UniProtP38169|KMO_YEAST Kynurenine 3-monooxygenase (Gene Name=BNA4)

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