Structure of PDB 4j1v Chain A

Receptor sequence
>4j1vA (length=166) Species: 9606 (Homo sapiens) [Search protein sequence]
LRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAG
PRYEYHWADPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMS
VAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLI
DRRELAPLQELIEKLG
3D structure
PDB4j1v Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction.
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A P91 R92 Y93 E94 Y95 H96 D99 Y114 R154 R157 R199 P51 R52 Y53 E54 Y55 H56 D59 Y68 R108 R111 R153
BS02 peptide A Y163 F167 E176 A177 N180 T181 K210 L211 Y117 F121 E130 A131 N134 T135 K164 L165
BS03 ZN A C79 C84 H161 H166 C39 C44 H115 H120
External links
PDB RCSB:4j1v, PDBe:4j1v, PDBj:4j1v
PDBsum4j1v
PubMed25031347
UniProtQ9H8S9|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)

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