Structure of PDB 4j16 Chain A

Receptor sequence
>4j16A (length=372) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence]
MVTVAVPKERAPGERRVALVPEVVARLVKGGARVRVERGAGEGAYHPDEA
YQEAGAEVVERGELLKGAHLLFTVQPPPEDLIQALEPGAIVVGFVQPHKN
LELVRALQAKKATVIAMELIPRITRAQSMDALSSQATVAGYLAAIHAARL
SPRFFPMLTTAAGTIRPAKVMVMGVGVAGLMAIATAKRLGAQVFAYDVRK
AALEQALSLGAKPIELPISAEGEGGYARELTEEEKRIQHEALRDHVAGMD
VLITTAQVPGRRAPILLTEDMVERLKPGTVVVDLAAESGGNCVLTKPGEV
VEVRGVRVYGPLNLPSELSVHASEMYAKNLYNLSSLLIEKGAFAPKWEDE
IVRAALLMKEGEVLHGPTKALL
3D structure
PDB4j16 Crystal structure analysis of Thermus thermophilus transhydrogenase soluble domains
ChainA
Resolution2.41 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R16 Q75 F94 Q96 E118 R122 Q127 D130 S133 E287
Catalytic site (residue number reindexed from 1) R16 Q75 F94 Q96 E118 R122 Q127 D130 S133 E287
Enzyme Commision number 7.1.1.1: proton-translocating NAD(P)(+) transhydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A R122 V175 G176 D197 R199 Q257 R122 V175 G176 D197 R199 Q257
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0006740 NADPH regeneration
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4j16, PDBe:4j16, PDBj:4j16
PDBsum4j16
PubMed
UniProtQ72GR8

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