Structure of PDB 4izv Chain A

Receptor sequence
>4izvA (length=262) Species: 501897 (Nesterenkonia sp. 10004) [Search protein sequence]
GLVPRGSHMRIALMQHTARPLDPQHNLDLIDDAAARASEQGAQLLLTPQL
FGFGYVPSQICAQVSAEQVDAARSRLRGIARDRGIALVWSLPGPEGPEQR
GITAELADEHGEVLASYQKVQLYGPEEKAAFVPGEQPPPVLSWGGRQLSL
LVAYDVEFPEMVRAAAARGAQLVLVPTALAGDETSVPGILLPARAVENGI
TLAYANHCGPEGGLVFDGGSVVVGPAGQPLGELGVEPGLLVVDLPDADYL
QDRRAELHRNWL
3D structure
PDB4izv Covalent modifications of the active site cysteine occur as a result of mutating the glutamate of the catalytic triad in the amidase from Nesterenkonia sp.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.4: amidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ROP A C53 P89 E90 C61 P97 E98
BS02 1HC A Q41 K111 Y115 A145 Y146 Q49 K119 Y123 A153 Y154
BS03 1HC A D14 P15 Q16 D22 P23 Q24
Gene Ontology
Molecular Function
GO:0004040 amidase activity
GO:0016787 hydrolase activity
GO:0043864 indoleacetamide hydrolase activity
GO:0050126 N-carbamoylputrescine amidase activity
Biological Process
GO:0033388 putrescine biosynthetic process from arginine

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Molecular Function
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Biological Process
External links
PDB RCSB:4izv, PDBe:4izv, PDBj:4izv
PDBsum4izv
PubMed
UniProtD0VWZ1

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