Structure of PDB 4ixd Chain A

Receptor sequence
>4ixdA (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
GNVDLVFLFDGSMSLQPDEFQKILDFMKDVMKKLSNTSYQFAAVQFSTSY
KTEFDFSDYVKWKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGAR
PDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKF
ASKPASEFVKILDTFEKLKDLFTELQKKIYVI
3D structure
PDB4ixd Identification and x-ray structure based investigation of an ICAM-1 binding enhancing small molecule activator of LFA-1
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A S139 S141 D239 S12 S14 D112
BS02 1HV A Y166 I235 Y257 E301 L302 Y39 I108 Y130 E174 L175
External links
PDB RCSB:4ixd, PDBe:4ixd, PDBj:4ixd
PDBsum4ixd
PubMed
UniProtP20701|ITAL_HUMAN Integrin alpha-L (Gene Name=ITGAL)

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