Structure of PDB 4ix2 Chain A

Receptor sequence
>4ix2A (length=334) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]
MLRIAKEALTFDDVLLVPAHSTVLPNTADLRTRLTKNIALNIPMVSASMD
TVTEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKISGGLRVGAAVGA
APGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGG
NVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAG
VANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVIL
YQGRSYKAYRGMPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVE
DLRTKAQFVRISGAGMKESHVHDVQITKEAPNYR
3D structure
PDB4ix2 Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, complexed with IMP.
ChainA
Resolution2.146 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.205: IMP dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP A M51 G304 S305 I306 D340 M361 G363 S364 Y387 M390 E417 M49 G176 S177 I178 D212 M233 G235 S236 Y259 M262 E264
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003938 IMP dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4ix2, PDBe:4ix2, PDBj:4ix2
PDBsum4ix2
PubMed
UniProtQ9KTW3

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