Structure of PDB 4iwn Chain A

Receptor sequence
>4iwnA (length=229) Species: 562 (Escherichia coli) [Search protein sequence]
TFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLG
AATLSVRRNIHHDNCKIIAIDNSPAMIERCRHHIDAYKAPTPVDVIEGDI
RDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSF
EDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
HNAGFEHSELWFQCFNFGSLVALKAEDAA
3D structure
PDB4iwn S-Adenosyl-S-carboxymethyl-L-homocysteine: a novel cofactor found in the putative tRNA-modifying enzyme CmoA.
ChainA
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.3.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GEK A F28 Y39 G64 S66 D89 N90 D117 I118 N132 F133 F137 R199 F10 Y21 G46 S48 D71 N72 D99 I100 N114 F115 F119 R181
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0016743 carboxyl- or carbamoyltransferase activity
GO:0042803 protein homodimerization activity
GO:1904047 S-adenosyl-L-methionine binding
Biological Process
GO:0002098 tRNA wobble uridine modification
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4iwn, PDBe:4iwn, PDBj:4iwn
PDBsum4iwn
PubMed23695253
UniProtP76290|CMOA_ECOLI Carboxy-S-adenosyl-L-methionine synthase (Gene Name=cmoA)

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