Structure of PDB 4iui Chain A

Receptor sequence
>4iuiA (length=211) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEEASMMGLLTNLADRELVHMINWAK
RVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDR
NQGKMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYIHRVLDK
ITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCS
DLLLEMLDAHR
3D structure
PDB4iui Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 L372 V376 E380 E542 I46 L60 V64 E68 E205
BS02 1GQ A M343 L346 E353 L387 M388 L391 R394 M421 F425 G521 H524 M31 L34 E41 L75 M76 L79 R82 M105 F109 G190 H193
External links
PDB RCSB:4iui, PDBe:4iui, PDBj:4iui
PDBsum4iui
PubMed23524984
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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