Structure of PDB 4iuf Chain A

Receptor sequence
>4iufA (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
TSDLIVLGLPWKTTEQDLKEYFSTFGEVLMVQVKKDLKTGHSKGFGFVRF
TEYETQVKVMSQRHMIDGRWCDCKLPN
3D structure
PDB4iuf The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.
ChainA
Resolution2.752 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A D105 I107 L109 G110 L111 W113 K136 G146 F149 R171 K176 P178 N179 D3 I5 L7 G8 L9 W11 K34 G44 F47 R69 K74 P76 N77
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:4iuf, PDBe:4iuf, PDBj:4iuf
PDBsum4iuf
PubMed24464995
UniProtQ13148|TADBP_HUMAN TAR DNA-binding protein 43 (Gene Name=TARDBP)

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