Structure of PDB 4itz Chain A

Receptor sequence
>4itzA (length=121) Species: 5855 (Plasmodium vivax) [Search protein sequence]
LEQVHLTEDGGVVKTILRKGEGGEENAPKKGNEVTVHYVGKLESSGKVFD
SSRERNVPFKFHLGQGEVIKGWDICVASMTKNEKCSVRLDSKYGYGEEGC
GESIPGNSVLIFEIELISFRE
3D structure
PDB4itz Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax.
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y43 F54 D55 I74 Y100 F117
Catalytic site (residue number reindexed from 1) Y38 F49 D50 I69 Y95 F112
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y43 D55 V73 I74 W77 Y100 C105 Y38 D50 V68 I69 W72 Y95 C100
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity

View graph for
Molecular Function
External links
PDB RCSB:4itz, PDBe:4itz, PDBj:4itz
PDBsum4itz
PubMed23435727
UniProtA5K8X6

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