Structure of PDB 4irs Chain A

Receptor sequence
>4irsA (length=268) Species: 10090 (Mus musculus) [Search protein sequence]
KNYTFRCLQMSSFANRSWSRTDSVVWLGDLQTHRWSNDSATISFTKPWSQ
GKLSNQQWEKLQHMFQVYRVSFTRDIQELVKMMSPKEDYPIEIQLSAGCE
MYPGNASESFLHVAFQGKYVVRFWGTSWQTVPGAPSWLDLPIKVLNADQG
TSATVQMLLNDTCPLFVRGLLEAGKSDLEKQEKPVAWLSSVPRQLVCHVS
GFYPKPVWVMWMRGDQEQQGTHRGDFLPNADETWYLQATLDVEAGEEAGL
ACRVKHSSLGGQDIILYW
3D structure
PDB4irs Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FUL A S114 F128 W129 G130 S109 F123 W124 G125
BS02 1LA A C12 Y73 S76 D80 W133 D153 T156 V160 C7 Y68 S71 D75 W128 D148 T151 V155
External links
PDB RCSB:4irs, PDBe:4irs, PDBj:4irs
PDBsum4irs
PubMed23960235
UniProtP11609|CD1D1_MOUSE Antigen-presenting glycoprotein CD1d1 (Gene Name=Cd1d1)

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