Structure of PDB 4ir5 Chain A

Receptor sequence
>4ir5A (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVI
KKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGH
NMRKYFEKKWTDTFKV
3D structure
PDB4ir5 Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IR5 A P1888 V1893 N1894 L1897 V1898 N1944 I1950 P33 V38 N39 L42 V43 N89 I95 PDBbind-CN: -logKd/Ki=6.21,IC50=0.61uM
BindingDB: IC50=610nM
External links
PDB RCSB:4ir5, PDBe:4ir5, PDBj:4ir5
PDBsum4ir5
PubMed25799074
UniProtQ9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (Gene Name=BAZ2B)

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