Structure of PDB 4io5 Chain A

Receptor sequence
>4io5A (length=242) Species: 104782 (Adineta vaga) [Search protein sequence]
GSARLKGITLRIGVIESVPFTIVANVNTTKLTGYVLDLIEYLRDKMGFVA
DVQLAPPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSISDNS
MRILMRKGTLIDGMDDLKNGKIPYNRIGIRIGTAGEDYYLREISGGSRNF
YPLKSRQEMYDSLLAGIIDVSFMDIGTAEYVTNNIYCNLTLVGEDFDKST
FGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQTKACP
3D structure
PDB4io5 Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
ChainA
Resolution1.721 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ALA A Y67 I86 T87 R92 T139 D180 Y61 I80 T81 R86 T133 D174 MOAD: Kd=9uM
PDBbind-CN: -logKd/Ki=5.03,Kd=9.27uM
BS02 CL A R93 K213 R87 K207
BS03 CL A S101 R229 S95 R223
BS04 CL A R136 D180 R130 D174
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4io5, PDBe:4io5, PDBj:4io5
PDBsum4io5
PubMed23434404
UniProtE9P5T5

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