Structure of PDB 4io4 Chain A

Receptor sequence
>4io4A (length=244) Species: 104782 (Adineta vaga) [Search protein sequence]
SARLKGITLRIGVIESVPFTIVANVIDRNTTKLTGYVLDLIEYLRDKMGF
VADVQLAPPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSISD
NSMRILMRKGTLIDGMDDLKNGKIPYNRIGIRIGTAGEDYYLREISGGSR
NFYPLKSRQEMYDSLLAGIIDVSFMDIGTAEYVTNNIYCNLTLVGEDFDK
STFGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQTKACP
3D structure
PDB4io4 Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
ChainA
Resolution1.941 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SER A Y67 T87 R92 T139 D180 Y63 T83 R88 T135 D176 MOAD: Kd=24uM
PDBbind-CN: -logKd/Ki=4.61,Kd=24.5uM
BS02 CL A R136 R162 M179 D180 R132 R158 M175 D176
BS03 CL A R93 K213 R89 K209
BS04 CL A Y192 N194 Y188 N190
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4io4, PDBe:4io4, PDBj:4io4
PDBsum4io4
PubMed23434404
UniProtE9P5T5

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