Structure of PDB 4io3 Chain A

Receptor sequence
>4io3A (length=242) Species: 104782 (Adineta vaga) [Search protein sequence]
GSARLKGITLRIGVIESVPFTIVANVNTTKLTGYVLDLIEYLRDKMGFVA
DVQLAPPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSISDNS
MRILMRKGTLIDGMDDLKNGKIPYNRIGIRIGTAGEDYYLREISGGSRNF
YPLKSRQEMYDSLLAGIIDVSFMDIGTAEYVTNNIYCNLTLVGEDFDKST
FGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQTKACP
3D structure
PDB4io3 Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
ChainA
Resolution1.66 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASP A Y67 I86 T87 R92 R136 T139 R162 D180 Y61 I80 T81 R86 R130 T133 R156 D174 MOAD: Kd=875nM
PDBbind-CN: -logKd/Ki=6.06,Kd=0.87uM
BS02 CL A R93 K213 R87 K207
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:4io3, PDBe:4io3, PDBj:4io3
PDBsum4io3
PubMed23434404
UniProtE9P5T5

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