Structure of PDB 4inb Chain A

Receptor sequence
>4inbA (length=146) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
PIVQNLQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQ
DLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPR
GSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
3D structure
PDB4inb Monitoring Binding of HIV-1 Capsid Assembly Inhibitors Using (19) F Ligand-and (15) N Protein-Based NMR and X-ray Crystallography: Early Hit Validation of a Benzodiazepine Series.
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1F6 A W23 V27 E28 A31 F32 S33 V36 F40 V59 G61 H62 A65 L138 I141 V142 W23 V27 E28 A31 F32 S33 V36 F40 V59 G61 H62 A65 L138 I141 V142 MOAD: ic50=0.89uM
PDBbind-CN: -logKd/Ki=6.05,IC50=0.89uM
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:4inb, PDBe:4inb, PDBj:4inb
PDBsum4inb
PubMed23401268
UniProtA9PKC6

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