Structure of PDB 4imb Chain A

Receptor sequence
>4imbA (length=301) Species: 4060 (Rauvolfia serpentina) [Search protein sequence]
KEILIEAPSYAPNSFTFDSTNKGFYTSVQDGRVIKYEGPNSGFVDFAYAS
PYWNKAFCENSTDAEKRPLCGRTYDISYNLQNNQLYIVDCYYHLSVVGSE
GGHATQLATSVDGVPFKWLYAVTVDQRTGIVYFTDVSTLYDDRGVQQIMD
TSDKTGRLIKYDPSTKETTLLLKELHVPGGAEVSADSSFVLVAEFLSHQI
VKYWLEGPKKGTAEVLVKIPNPGNIKRNADGHFWVSSSEELDGNMHGRVD
PKGIKFDEFGNILEVIPLPPPFAGEHFEQIQEHDGLLYIGTLFHGSVGIL
V
3D structure
PDB4imb Using Strictosidine Synthase to Prepare Novel Alkaloids.
ChainA
Resolution2.703 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) E309
Catalytic site (residue number reindexed from 1) E278
Enzyme Commision number 4.3.3.2: Transferred entry: 3.5.99.13.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1ES A V208 E309 V177 E278
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016844 strictosidine synthase activity
Biological Process
GO:0009058 biosynthetic process
GO:0009820 alkaloid metabolic process
Cellular Component
GO:0005773 vacuole
GO:0012505 endomembrane system

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4imb, PDBe:4imb, PDBj:4imb
PDBsum4imb
PubMed25850764
UniProtP68175|STSY_RAUSE Strictosidine synthase (Gene Name=STR1)

[Back to BioLiP]