Structure of PDB 4im7 Chain A

Receptor sequence
>4im7A (length=483) Species: 199310 (Escherichia coli CFT073) [Search protein sequence]
HLLSAKATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADILATEHFSDWG
YYEVNLIGGEQQIADLQQQDNLYTVAEMSADAWTARVVGVVKKALHVQID
GLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVVADVQNPH
QPKTATGVIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAI
DVKLAQWIEDNVTFPSTMVDRIVPAVTEDTLAKIEQLTGVRDAAGVACEP
FRQWVIEDNFVAGRPEWEKAGAELVSDVLPYEEMKLRMLNGSHSFLAYLG
YLAGYQHINDCMEDEHYRHAAYTLMLQEQAPTLKVQGVDLQDYANRLIER
YSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKFDLLALGVAGWM
RYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGTARVQSLLAIKAIFGDD
LPGNSLFTTKVTEAYLSLLAHGAKATVAKYSVK
3D structure
PDB4im7 Crystal structure of fructuronate reductase (ydfI) from E. coli CFT073 (EFI TARGET EFI-506389) complexed with NADH and D-mannonate
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CS2 A D224 K289 N294 H297 K374 R378 D220 K285 N290 H293 K370 R374
BS02 NAI A G29 F30 G31 A32 F33 N59 I61 G62 T124 I125 T126 G129 D184 N185 V223 R225 V227 G25 F26 G27 A28 F29 N55 I57 G58 T120 I121 T122 G125 D180 N181 V219 R221 V223
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Biological Process
GO:0019594 mannitol metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4im7, PDBe:4im7, PDBj:4im7
PDBsum4im7
PubMed
UniProtA0A0H2V7F2

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