Structure of PDB 4iho Chain A

Receptor sequence
>4ihoA (length=272) Species: 10090 (Mus musculus) [Search protein sequence]
GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAP
WMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSG
CDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQS
GAAEHYKAFLEGECVEWLHRYLKNGNATLRTDSPKAHVTHHPRSKGEVTL
RCWALGFYPADITLTWQEELTQDMELVETRPAGDGTFQKWASVVVPLGKE
QNYTCRVYHEGLPEPLTLRWEP
3D structure
PDB4iho Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 R62 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 T143 K146 W147 S150 A152 H155 Y156 F159 W167 Y171 Y7 R62 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 T143 K146 W147 S150 A152 H155 Y156 F159 W167 Y171
External links
PDB RCSB:4iho, PDBe:4iho, PDBj:4iho
PDBsum4iho
PubMed23939911
UniProtP01899|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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