Structure of PDB 4igq Chain A

Receptor sequence
>4igqA (length=273) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence]
AKWNPAGARRPVLDEAPVFYPTEEEFEDTLKYIESIRPMAEPYGICRIVP
PSSWKPDKSIWEGSKFSTRVQKVDKLQNRKFGFEPGPEFTLQTFQKYADD
FSKQYFVPSVEDIEGEYWRIVEVPTEEIEVIYGADLETGAQSGWNLNNLP
RLLVPWVYVGMCFSSFCWHVEDHHLYSLNYMHWGAPKLWYGVPGKDAVNL
ESAMRKHLPELFEEQPDLLHNLVTQFSPSLLKSEGVHVYRCVQHEGEFVL
TFPRAYHAGFNCGFNCAEAVNVA
3D structure
PDB4igq Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
ChainA
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y383 H394 E396 H482 A494
Catalytic site (residue number reindexed from 1) Y158 H169 E171 H257 A269
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D324 W381 Y383 H394 V395 E396 D397 S402 L447 A494 V495 N496 D135 W156 Y158 H169 V170 E171 D172 S177 L222 A269 V270 N271
BS02 FE A H394 E396 H482 H169 E171 H257
BS03 OGA A Y383 F391 H394 S402 N404 K412 H482 Y158 F166 H169 S177 N179 K187 H257
External links
PDB RCSB:4igq, PDBe:4igq, PDBj:4igq
PDBsum4igq
PubMed23357881
UniProtQ53WJ1|JM703_ORYSJ Lysine-specific demethylase JMJ703 (Gene Name=JMJ703)

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