Structure of PDB 4igo Chain A

Receptor sequence
>4igoA (length=270) Species: 39947 (Oryza sativa Japonica Group) [Search protein sequence]
AKWNPAGARRPVLDEAPVFYPTEEEFEDTLKYIESIRPMAEPYGICRIVP
PSSWKPDKSIWEGSKFSTRVQKVDKLQNRKFGFEPGPEFTLQTFQKYADD
FSKQYFVPSVEDIEGEYWRIVEVPTEEIEVIYGADLAQSGWNLNNLPRLL
VPWVYVGMCFSSFCWHVEDHHLYSLNYMHWGAPKLWYGVPGKDAVNLESA
MRKHLPELFEEQPDLLHNLVTQFSPSLLKSEGVHVYRCVQHEGEFVLTFP
RAYHAGFNCGFNCAEAVNVA
3D structure
PDB4igo Structural basis of a histone H3 lysine 4 demethylase required for stem elongation in rice.
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y383 H394 E396 H482 A494
Catalytic site (residue number reindexed from 1) Y155 H166 E168 H254 A266
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H394 E396 H482 H166 E168 H254
BS02 AKG A Y383 F391 H394 E396 N404 H482 Y155 F163 H166 E168 N176 H254
External links
PDB RCSB:4igo, PDBe:4igo, PDBj:4igo
PDBsum4igo
PubMed23357881
UniProtQ53WJ1|JM703_ORYSJ Lysine-specific demethylase JMJ703 (Gene Name=JMJ703)

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