Structure of PDB 4idp Chain A

Receptor sequence
>4idpA (length=416) Species: 9606 (Homo sapiens) [Search protein sequence]
KAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKGK
SFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEIF
LINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQ
NVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGAD
GGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNP
NFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYFK
AYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKP
FLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYI
QYIKHNDSKTIFHAAR
3D structure
PDB4idp Structural basis for conformational switching and GTP loading of the large G protein atlastin.
ChainA
Resolution2.587 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A F76 R77 K78 G79 K80 S81 F82 W112 R113 G114 R118 E119 T120 G149 R217 D218 P272 V276 F46 R47 K48 G49 K50 S51 F52 W82 R83 G84 R88 E89 T90 G119 R187 D188 P242 V246
BS02 MG A S81 T120 S51 T90
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4idp, PDBe:4idp, PDBj:4idp
PDBsum4idp
PubMed23334294
UniProtQ8WXF7|ATLA1_HUMAN Atlastin-1 (Gene Name=ATL1)

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