Structure of PDB 4idn Chain A

Receptor sequence
>4idnA (length=417) Species: 9606 (Homo sapiens) [Search protein sequence]
KKAGPVQVLIVKDDHSFELDETALNRILLSEAVRDKEVVAVSVAGAFRKG
KSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEI
FLINKPDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLS
QNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGA
DGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATN
PNFDGKLKEIDDEFIKNLKILIPWLLSPESLDIKEINGNKITCRGLVEYF
KAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDK
PFLAPNDLQTKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELY
IQYIKHNDSKNIFHAAR
3D structure
PDB4idn Structural basis for conformational switching and GTP loading of the large G protein atlastin.
ChainA
Resolution2.252 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A F76 R77 G79 K80 S81 F82 W112 R113 R118 E119 T120 R217 D218 P272 V276 F47 R48 G50 K51 S52 F53 W83 R84 R89 E90 T91 R188 D189 P243 V247 MOAD: Kd=5.77uM
PDBbind-CN: -logKd/Ki=5.24,Kd=5.77uM
BS02 MG A S81 T120 S52 T91
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4idn, PDBe:4idn, PDBj:4idn
PDBsum4idn
PubMed23334294
UniProtQ8WXF7|ATLA1_HUMAN Atlastin-1 (Gene Name=ATL1)

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