Structure of PDB 4icq Chain A

Receptor sequence
>4icqA (length=413) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence]
MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHLIVKEAY
ALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASR
LGVRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAA
GLEWAKKVFPNAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKS
KADMLNKEQFSALHYTAPGTDLTLGLPKNHVWESAGAVNAQGEEFLPNMP
TEEVFTAPDFRRADGYVTSTKPLSYNGNIIEGIKVTFKDGQIVDITAEKG
DQVMKDLVFENAGARALGECALVPDPSPISQSGITFFNTLFDENASNHLA
IGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMDIDGIREDG
TRVPLFRNGNWAN
3D structure
PDB4icq Structure-based elucidation of the regulatory mechanism for aminopeptidase activity.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A E319 Y355 H381 D383 E319 Y355 H381 D383
BS02 ZN A E253 E319 H348 E253 E319 H348
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4icq, PDBe:4icq, PDBj:4icq
PDBsum4icq
PubMed23999297
UniProtA0A0H2UN95

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