Structure of PDB 4ibk Chain A

Receptor sequence
>4ibkA (length=123) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
DISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASL
AEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPS
PKIDRGWVCVFQLQDGKTLGLKI
3D structure
PDB4ibk In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1DE A Q241 Q244 V245 K248 K251 P293 I295 D302 F328 Q24 Q27 V28 K31 K34 P76 I78 D85 F111 MOAD: Kd=50.4uM
PDBbind-CN: -logKd/Ki=4.30,Kd=50.4uM
External links
PDB RCSB:4ibk, PDBe:4ibk, PDBj:4ibk
PDBsum4ibk
PubMed24495995
UniProtQ05127|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)

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