Structure of PDB 4ibj Chain A

Receptor sequence
>4ibjA (length=124) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
PDISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQAS
LAEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPP
SPKIDRGWVCVFQLQDGKTLGLKI
3D structure
PDB4ibj In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
ChainA
Resolution1.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1D9 A K222 Q241 Q244 K248 K251 I295 F328 K6 Q25 Q28 K32 K35 I79 F112 MOAD: Kd=47uM
PDBbind-CN: -logKd/Ki=4.33,Kd=47.0uM
External links
PDB RCSB:4ibj, PDBe:4ibj, PDBj:4ibj
PDBsum4ibj
PubMed24495995
UniProtQ05127|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)

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