Structure of PDB 4ibb Chain A

Receptor sequence
>4ibbA (length=123) Species: 128952 (Ebola virus - Mayinga, Zaire, 1976) [Search protein sequence]
DISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASL
AEGDSPQCALIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPS
PKIDRGWVCVFQLQDGKTLGLKI
3D structure
PDB4ibb In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
ChainA
Resolution1.752 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1DK A A221 Q241 Q244 K248 K251 I295 A4 Q24 Q27 K31 K34 I78 MOAD: Kd=270.7uM
PDBbind-CN: -logKd/Ki=3.57,Kd=270.7uM
External links
PDB RCSB:4ibb, PDBe:4ibb, PDBj:4ibb
PDBsum4ibb
PubMed24495995
UniProtQ05127|VP35_EBOZM Polymerase cofactor VP35 (Gene Name=VP35)

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