Structure of PDB 4i2w Chain A

Receptor sequence
>4i2wA (length=904) Species: 6239 (Caenorhabditis elegans) [Search protein sequence]
VQTAEEIRDEGNAAVKDQDYIKADELYTEALQLTTDEDKALRPVLYRNRA
MARLKRDDFEGAQSDCTKALEFDGADVKALFRRSLAREQLGNVGPAFQDA
KEALRLSPNDKGIVEVLQRLVKANNDKIKQTTSLANKVTDMEKLAFRGEA
KDTEQKMTALNNLLVLCRESESGATGVWNQGALVPFVLNLINDASENEEV
TVTAIRILDETIKNSVRCMKFLAMHDPDGPKSVRFVCRLMCKKSTKDFVD
ATGILVQRVFNAMAKMDRQKEMKPDPEVAEANKIWIIRVLLELQEMLQDP
KVGAVQRETCIDLFLKNLMHMDGGIPRGWSWKFVEERGLLALLDVASQIP
ELCEYPVSAETRQHVAICLQRLEEDMVFDTKRTIFKEKVDMFFNALISRC
TNDDEGHKYRIKLSCFLITMLQGPVDIGINLITNDQLTPIMLEMAASQDH
LMQGIAAELIVATVSKHERAINMLKVGIPVLRALYDSEDPTVKVRALVGL
CKIGAEEAVISLAKTCKKFLLETEKYSVDIRRYACEGLSYLSLDADVKEW
IVDDSLLLKALVLLAKKAGALCVYTLATIYANLSNAFEKPKFAKHHVPET
HPKDTEEYVEKRVRALVEEGAVPACVAVSKTESKNALELIARSLLAFAEY
EDLRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGAKADPMISFPG
QRAYEVVKPLCDLLHPDVEGKANYDSLLTLTNLASVSDSIRGRILKEKAI
PKIEEFWFMTDHEHLRAAAAELLLNLLFFEKFYEETVAPGTDRLKLWVLY
SAEVEEERLSRASAAGFAILTEDENACARIMDEIKSWPEVFKDIAMHEDA
ETQRRGLMGIANIMHSSNKLCSEIVSSEVFRVLVAVTKLGTINQERAGST
EQAK
3D structure
PDB4i2w The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans.
ChainA
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R12 N16 Y31 V48 N52 K59 K82 F85 R86 R8 N12 Y27 V44 N48 K55 K78 F81 R82
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0042802 identical protein binding
GO:0044183 protein folding chaperone
GO:0051879 Hsp90 protein binding
Biological Process
GO:0007517 muscle organ development
GO:0009792 embryo development ending in birth or egg hatching
GO:0018991 egg-laying behavior
GO:0030154 cell differentiation
GO:0040011 locomotion
GO:0045214 sarcomere organization
GO:0061077 chaperone-mediated protein folding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0032154 cleavage furrow
GO:0048471 perinuclear region of cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4i2w, PDBe:4i2w, PDBj:4i2w
PDBsum4i2w
PubMed23332754
UniProtG5EG62

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