Structure of PDB 4i1p Chain A

Receptor sequence
>4i1pA (length=379) Species: 9606 (Homo sapiens) [Search protein sequence]
MLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLT
EYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSE
NCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIV
FGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMG
KCHLTKGKQALEIRSSLSEKRALTDPIQGTEYSAESLVRNLQWAKAHELP
ESMCLKFDCGVQIQLGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPL
DLDIDPKDANKGTPEETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFTVC
LSYQYSGLEDTVEDKQEVNVGKPLIAKLD
3D structure
PDB4i1p Activity-Based Probes for Detection of Active MALT1 Paracaspase in Immune Cells and Lymphomas.
ChainA
Resolution2.403 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A A361 P362 D365 H415 D462 C464 E497 A498 F499 E500 Q502 A24 P25 D28 H78 D125 C127 E160 A161 F162 E163 Q165
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4i1p, PDBe:4i1p, PDBj:4i1p
PDBsum4i1p
PubMed25556945
UniProtQ9UDY8|MALT1_HUMAN Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Gene Name=MALT1)

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