Structure of PDB 4hxy Chain A

Receptor sequence
>4hxyA (length=425) Species: 244967 (Streptomyces sp. HK803) [Search protein sequence]
RTGWFSETWRQLGTADRVPGNWLLLGEVPPALGSLFDDPLTAASWDRSTA
PDGVLVGAGAAEDLLAALHEVAGHPTGPVWCVTSRAVGVGTVDDPAADVR
AAGVWGLGRVAGLELPDRWGGLVDLPERIDDATRRALAGTLTDGEDQLAV
RDGQLWARRLVTTPAPQTGTWTPKGTVLITGGTGGLGGHVARRVAEQGSA
DRILLLSRQGSAAPGATELLEGIRAFGATAEAVAVDVTDRAAMSGLIDAL
AAEGAPVRTVVHAAGVVRDVRIAETGAEELAAQMAAKVEGALLLDELLPD
LDDFVLFSSISGIWGAAGQAGYAAGNACLDALARRRREQGKRAVSVAWGP
WAGGGMLTEHDERELRKRGLTPLLVPAALQAMEQAIMSDRAGDPVVADVT
WSRFLPAFTASRPSPLFGSFEEKAA
3D structure
PDB4hxy Structural and Stereochemical Analysis of a Modular Polyketide Synthase Ketoreductase Domain Required for the Generation of a cis-Alkene.
ChainA
Resolution1.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NDP A G191 G194 G195 L196 S217 R218 Q219 D246 V247 A273 A274 G275 A296 K297 S318 Y332 W358 P360 G365 M366 G181 G184 G185 L186 S207 R208 Q209 D236 V237 A263 A264 G265 A286 K287 S308 Y322 W348 P350 G355 M356
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