Structure of PDB 4hvl Chain A

Receptor sequence
>4hvlA (length=369) Species: 1078020 (Mycolicibacterium thermoresistibile ATCC 19527) [Search protein sequence]
MIEPPVIDPAAVPPDETGPDNPMEQRRVCAAPTVYPDSNFADRPWASDYL
RLTEAHKFATGAGITVAVIDTGVNGSPRVPAEPGGDFVDAAGNGMSDCDA
HGTLTASVIAGRGAPTDGFIGVAPDARILSLRHTSAAFQPVGARTDPNNP
NTTQTAGSLRSLARAIVHAANLGAQVINISEAACYKVTRPIDETGVGAAV
NYAVHVKNAVVIAAAGNTGQDCTQNPPPDPAVPSDPRGWQQVQTIVSPAW
YSPLVLTVGGIGPTGQPSNFSMSGPWVGAAAPAENITALGYGGEPVNALQ
GQDGLVPVAGTSFAAAYVSGLAALIRQRYPDLTPAQVINRITATARHPGG
GVDNYVGAGVIDPVAALTW
3D structure
PDB4hvl Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D92 H123 N239 S334
Catalytic site (residue number reindexed from 1) D70 H101 N217 S312
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H155 T156 E203 H133 T134 E181
BS02 ZN A D37 H190 D15 H168
BS03 ZN A H123 S334 H101 S312
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4hvl, PDBe:4hvl, PDBj:4hvl
PDBsum4hvl
PubMed24113528
UniProtG7CDQ2

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