Structure of PDB 4hue Chain A

Receptor sequence
>4hueA (length=134) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence]
EEIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEF
LAIVHGLRYLKERNSRKPIYSNSQTAIKWVKDKKAKSTLVRNEETALIWK
LVDEAEEWLNTHTYETPILKWQTDKWGEIKADYG
3D structure
PDB4hue Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs.
ChainA
Resolution1.561 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A N77 T104 N106 W139 K146 S147 T148 N17 T44 N46 W79 K86 S87 T88
BS02 MG A D71 E109 D11 E49
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4hue, PDBe:4hue, PDBj:4hue
PDBsum4hue
PubMed23275540
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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