Structure of PDB 4hrq Chain A

Receptor sequence
>4hrqA (length=189) Species: 228410 (Nitrosomonas europaea ATCC 19718) [Search protein sequence]
MNDALHIGLPPFLVQANNEPRVLAAPEARMGYVLELVRANIAADGGPFAA
AVFERDSGLLIAAGTNRVVPGRCSAAHAEILALSLAQAKLDTHDLSADGL
PACELVTSAEPCVMCFGAVIWSGVRSLVCAARSDDVEAIGFDEGPRPENW
MGGLEARGITVTTGLLRDAACALLREYNACNGVIYNARC
3D structure
PDB4hrq Identification of function and mechanistic insights of guanine deaminase from Nitrosomonas europaea: role of the C-terminal loop in catalysis
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 AZG A F48 N66 H77 E79 F48 N66 H77 E79
BS02 ZN A H77 C112 C115 H77 C112 C115
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0047974 guanosine deaminase activity
Biological Process
GO:0006152 purine nucleoside catabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4hrq, PDBe:4hrq, PDBj:4hrq
PDBsum4hrq
PubMed23557066
UniProtQ82Y41

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