Structure of PDB 4hn1 Chain A

Receptor sequence
>4hn1A (length=199) Species: 1896 (Streptomyces bikiniensis) [Search protein sequence]
MHPLSIEGAWSQEPVIHSDHRGRSHEWFRGESFRQAFGHDFPVAQVNVAV
SHRGALRGINYTEIPPGQAKYSVCVRGAGLDVVVDVRIGSPTFGRWEIVP
MDAERNTAVYLTAGLGRAFLSLTDDATLVFLCSSGYAPAREHSVNPLDPD
LGIAWPDDIEPLLSDRDENAPTLATAERLGLLPTYQAWQEQQQAQRLEH
3D structure
PDB4hn1 Structural and Functional Studies on a 3'-Epimerase Involved in the Biosynthesis of dTDP-6-deoxy-d-allose.
ChainA
Resolution1.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N60 K70 F130 D167
Catalytic site (residue number reindexed from 1) N60 K70 F130 D167
Enzyme Commision number 5.1.3.27: dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TYD A R57 Y136 R57 Y136
BS02 TYD A H17 R21 E26 H17 R21 E26
Gene Ontology
Molecular Function
GO:0008830 dTDP-4-dehydrorhamnose 3,5-epimerase activity
GO:0016853 isomerase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:0019305 dTDP-rhamnose biosynthetic process
GO:0045226 extracellular polysaccharide biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:4hn1, PDBe:4hn1, PDBj:4hn1
PDBsum4hn1
PubMed23116432
UniProtQ5SFD1|CHMJ_STRBI dTDP-4-dehydro-6-deoxyglucose 3-epimerase (Gene Name=chmJ)

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