Structure of PDB 4hmx Chain A

Receptor sequence
>4hmxA (length=202) [Search protein sequence]
GSVDVLFPEYDDPPSEPITLLKRWLATADVARVREPKALALATATSDGRI
SSRVIAFSSIDDRGVIFCTHSTSRKGRELTETGWASGLLYWRETGQQIMI
SGQAVPLEESENDKLWFGRSVPMHAMSSASHQSDELVDREALRAHAAELL
ALGVALPRPPRFVGYRLEPHEMEFWAASSDRLHRRLRYERDGNDWKTTQL
QP
3D structure
PDB4hmx Trapped intermediates in crystals of the FMN-dependent oxidase PhzG provide insight into the final steps of phenazine biosynthesis
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.10.3.16: dihydrophenazinedicarboxylate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN A R63 V64 I65 A66 C78 T79 S83 R84 K85 Q142 S143 R53 V54 I55 A56 C68 T69 S73 R74 K75 Q132 S133
BS02 FMN A Y100 Q107 W185 R195 Y90 Q97 W175 R185
Gene Ontology
Molecular Function
GO:0004733 pyridoxamine phosphate oxidase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0002047 phenazine biosynthetic process
GO:0008615 pyridoxine biosynthetic process
GO:0017000 antibiotic biosynthetic process
GO:0042816 vitamin B6 metabolic process
GO:0042823 pyridoxal phosphate biosynthetic process
GO:1901615 organic hydroxy compound metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4hmx, PDBe:4hmx, PDBj:4hmx
PDBsum4hmx
PubMed23897464
UniProtQ396C5|PHZG_BURL3 Dihydrophenazinedicarboxylate synthase (Gene Name=phzG)

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