Structure of PDB 4hjw Chain A

Receptor sequence
>4hjwA (length=375) Species: 5530 (Metarhizium anisopliae) [Search protein sequence]
SMATSNPTVVDIHTHMYPPQYIKILESRTTIPLVRKFPQAPEPRLILLEA
ELGDLEKAINDPSAKPPGRPLTSHFASLDQKIHFMDTHRIDISVISLANP
WLDFVHASHAGDIAESVNDEFSDMCGKHHGRLFFFGTLPLTAPLETLLAS
ISHLAALKYCRGVILGTSGLGKGLDDPHLIPIFEALAAANLTIFLHPHYG
LPNDVWGPRAGEYGHVLPLALGFPMETTIAVARMYLAGVFDQVRDLRMVL
AHSGGTLPFLAGRIESCIFHDGQLVRQGKVGENRRTVWDVLKEQVYLDAV
IYSEVGLKAAIDASGSDRLMFGTDHPFFPPITTDEQGQWESVSLNAQAVA
EAVGEGSAEARAIMGSNAIRVLRLE
3D structure
PDB4hjw Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.1.66: uracil-5-carboxylate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H12 H14 H195 D323 H13 H15 H196 D324
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016831 carboxy-lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0019748 secondary metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4hjw, PDBe:4hjw, PDBj:4hjw
PDBsum4hjw
PubMed23917530
UniProtE9F0X0

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