Structure of PDB 4hdu Chain A

Receptor sequence
>4hduA (length=108) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
MRMDEFYTKVYDAVCEIPYGKVSTYGEIARYVGMPSYARQVGQAMKHLHP
ETHVPWHRVINSRGTISKRDISAGEQRQKDRLEEEGVEIYQTSLGEYKLN
LPEYMWKP
3D structure
PDB4hdu Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-{pi} interactions.
ChainA
Resolution2.848 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y25 G26 R39 M45 K46 W56 N61 S62 S67 K68 R69 D70 Y25 G26 R39 M45 K46 W56 N61 S62 S67 K68 R69 D70 PDBbind-CN: Kd=9.3nM
BS02 dna A M3 S36 Y37 Q40 M3 S36 Y37 Q40 PDBbind-CN: Kd=9.3nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003824 catalytic activity
GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity
GO:0032132 O6-alkylguanine-DNA binding
Biological Process
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0070911 global genome nucleotide-excision repair
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:4hdu, PDBe:4hdu, PDBj:4hdu
PDBsum4hdu
PubMed23112169
UniProtQ9UTN9|ATL1_SCHPO Alkyltransferase-like protein 1 (Gene Name=atl1)

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