Structure of PDB 4hc7 Chain A

Receptor sequence
>4hc7A (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
HMGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRL
SAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMK
KEGIQTRN
3D structure
PDB4hc7 DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R330 R331 R365 N366 R72 R73 R107 N108
BS02 dna A T327 N340 L344 H349 R353 M357 Q363 T364 R365 T69 N82 L86 H91 R95 M99 Q105 T106 R107
BS03 ZN A C318 C321 C339 C342 C60 C63 C81 C84
BS04 ZN A C264 C267 C285 C288 C6 C9 C27 C30
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:4hc7, PDBe:4hc7, PDBj:4hc7
PDBsum4hc7
PubMed23142663
UniProtP23771|GATA3_HUMAN Trans-acting T-cell-specific transcription factor GATA-3 (Gene Name=GATA3)

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