Structure of PDB 4h9y Chain A

Receptor sequence
>4h9yA (length=318) Species: 235909 (Geobacillus kaustophilus HTA426) [Search protein sequence]
EMVETVCGPVPVEQLGKTLIHEHFLFGYPGFQGDVTRGTFREDESLRVAV
EAAEKMKRHGIQTVVDPTPNDCGRNPAFLRRVAEETGLNIICATGYYYPP
YFQFRRLLGTAEDDIYDMFMAELTEGIADTGIKAGVIKLASSKGRITEYE
KMFFRAAARAQKETGAVIITHTQEGTMGPEQAAYLLEHGADPKKIVIGHM
CGNTDPDYHRKTLAYGVYIAFDRFGIQGMVGAPTDEERVRTLLALLRDGY
EKQIMLSHDTVNVWLGRPFTLPEPFAEMMKNWHVEHLFVNIIPALKNEGI
RDEVLEQMFIGNPAALFS
3D structure
PDB4h9y Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase.
ChainA
Resolution2.085 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H23 H25 K145 H178 H206 G209 R230 D266
Catalytic site (residue number reindexed from 1) H21 H23 K138 H171 H199 G202 R223 D259
Enzyme Commision number 3.5.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A H23 H25 K145 D266 H21 H23 K138 D259
BS02 ZN A K145 H178 H206 K138 H171 H199
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009056 catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4h9y, PDBe:4h9y, PDBj:4h9y
PDBsum4h9y
PubMed23461395
UniProtQ5KZU5

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